Abstract: The electricity usage mode of dispatchable resources for distribution network and its sensitivity to excitation signals are greatly different, which will directly influence the operability, operating efficiency and operating benefit of interactive resources dispatching. In this paper, according to such factors as weekday and holiday operation mode, coordinative optimization of planned maintenance, optimization of temporary power supply and power guarantee demand of important load, the multiple interactive operations are divided into different scenes to study interactive technology among long-and-medium-term distribution network, distributed generators, load and higher level power grid. An in-depth study of the objective, model and method for monthly operation structure optimization is carried out, and the operation structure optimization of actual Nanjing distribution network is solved by multi-objective particle swarm optimization(MOPSO) algorithm. The optimal reference scheme is obtained from the solution sets of monthly operation structure optimization, which verifies the correctness and validity of proposed method.