Abstract: Based on developing trends of the energy internet, the developing challenge of multi-energy system for regional energy internet is deeply analyzed, and corresponding planning and decision-making are studied. In addition, solving methods for such real requirements as energy planning for multi-energy system, response modeling, dispatch analysis of multi-energy bus and system operation development are designed. Furthermore, information and communication support system is built based on “Big Data-Cloud Computing-Internet of Things-Mobile Internet” new technique to achieve the information sharing for multi-energy system. On the basis of real requirement of Zhejiang energy internet, critical technique of multi-energy system planning and decision-making for energy internet are verified through cases study, which include business structure, data structure, technique framework and system allocation, etc. This work provides reference for system realization of multi-energy coordinated planning, optimized control and scientific evaluation for energy internet.