Abstract: To ensure reliable and economic operation of regional energy Internet, based on chance constraint theory the optimal operation method under uncertain environment was researched. Considering stochastic variables in wind power output forecasting error, the reserve capacity chance constraint condition for gas turbine and the objective function of reserve deviation risk cost were established, and then, a stochastic optimization operation method of regional energy Internet considering reserve capacity was proposed. Simulation results show that the proposed method can effectively control the operation risks caused by wind power integration, improve the reliability of system operation, and ensure the economy of system operation and gas turbine reservation.