Abstract: Under the background of the goal of "carbon peaking and carbon neutrality", further improvement in the economy and low carbon of the operation of the integrated energy system (IES) is a crucial factor in facilitating the clean energy transformation and upgrading. Firstly, an integrated demand response (IDR) generalized demand response (IDR) is proposed. The organic Rankine Cycle (ORC)-waste heat boiler (WHB) equipment is introduced on the source side, while to achieve the interactive response of both supply and demand in IES, the user electric heat IDR is used on the load side. On this basis, a more flexible carbon capture operation mode is proposed, wherein the remaining power after the system coordination and dispatch is utilized for systematic carbon capture. Finally, with the objective of minimizing the overall cost of the system, a thermoelectric coupling IES economic low-carbon optimal scheduling model is constructed. Additionally, the issue of uncertainty in wind and solar output is addressed based on the opportunity constraint planning of sequence operations. The simulation demonstrates that compared with the traditional thermoelectric coupling IES model, the proposed model can significantly reduce the total operating cost and carbon emission of IES. Moreover, it can promote the consumption of new energy within the system.